[1]肖美添,叶静,汤须崇,等.江蓠藻膳食纤维的降血糖及抗氧化作用[J].华侨大学学报(自然科学版),2009,30(6):665-667.[doi:10.11830/ISSN.1000-5013.2009.06.0665]
　XIAO Mei-tian,YE Jing,TANG Xu-chong,et al.Study on Lowering Blood Glucose and Anti-Oxidation of Dietary Fiber from Gracilaria[J].Journal of Huaqiao University(Natural Science),2009,30(6):665-667.[doi:10.11830/ISSN.1000-5013.2009.06.0665]
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江蓠藻膳食纤维的降血糖及抗氧化作用()
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《华侨大学学报（自然科学版）》[ISSN:1000-5013/CN:35-1079/N]

卷:
第30卷
期数:
2009年第6期
页码:
665-667
栏目:
出版日期:
2009-11-20

文章信息/Info

Title:
Study on Lowering Blood Glucose and Anti-Oxidation of Dietary Fiber from Gracilaria
文章编号:
1000-5013(2009)06-0665-03
作者:
肖美添; 叶静; 汤须崇; 刘青; 黄雅燕
华侨大学化工学院
Author(s):
XIAO Mei-tian;  YE Jing;  TANG Xu-chong;  LIU Qing;  HUANG Ya-yan
College of Chemical Engineering, Huaqiao University, Quanzhou 362021, China
关键词:
江蓠;  膳食纤维;  糖尿病;  血糖;  抗氧化
Keywords:
Gracilaria;  dietary fiber;  diabetes;  blood glucose;  anti-oxidation
分类号:
R151; R587.1
DOI:
10.11830/ISSN.1000-5013.2009.06.0665
文献标志码:
A
摘要:
观察江蓠藻膳食纤维对糖尿病小鼠的血糖,以及血清中某些抗氧化指标的效应,探讨其降血糖的可能作用机理.结果表明,江蓠藻膳食纤维能显著降低四氧嘧啶糖尿病小鼠的血糖值,且以中剂量(0.4 g.kg-1)江蓠藻膳食纤维的降血糖作用最佳.此外,江蓠藻膳食纤维可降低四氧嘧啶糖尿病小鼠血清中的丙二醛(MDA)浓度,提高超氧化物歧化酶(SOD)活性,改善糖尿病小鼠的氧化应激水平.
Abstract:
The effects of dietary fiber from Gracilaria(GDF) on blood glucose in diabetic mice and some anti-oxidative indexes in the serum were observed,and the mechanism of GDF lowering blood glucose was also discussd.The results indicated that GDF could obviously decrease the blood glucose levels of alloxan-induced diabetic mice,and the hypoglycemic effect of GDF at the middle dose of 0.4 g·kg-1 was the best.Moreover,GDF could significantly decrease the content of malondialdehyde(MDA) in the serum of alloxan-induced diabetic mice,increase the activity of superoxide dismutase(SOD) and improve the oxidative stress levels of diabetic mice.

参考文献/References:

[1] 黄森. 氧自由基与糖尿病发病机制 [J]. 实用临床医学, 2006(4):146-147.doi:10.3969/j.issn.1009-8194.2006.04.082.
[2] 徐淑云, 卞如濂, 陈修. 药理实验方法学 [M]. 北京:人民卫生出版社, 2002.1472-1523.
[3] GIACCO R, CLEMENTE G, RICCARD G. Dietary fiber in treatment of diabetes:Myth or reality [J]. Digestive and Liver Disease, 2002(2):140-144.
[4] 叶蕻芝, 许雪琴, 林薇. 三白草对四氧嘧啶型糖尿病小鼠治疗作用的实验研究 [J]. 福建中医学院学报, 2004(3):34-35.doi:10.3969/j.issn.1004-5627.2004.03.013.
[5] 王儒平, 张燕明. 糖尿病心肌梗塞与氧自由基研究概况 [J]. 深圳中西医结合杂志, 2004(2):118-121.doi:10.3969/j.issn.1007-0893.2004.02.024.
[6] 赵红, 张玉媛, 马儒林. 大豆异黄酮对高脂血症大鼠体内SOD、GSH-Px活力及MDA含量的影响 [J]. 实用全科医学, 2005(3):191-192.doi:10.3969/j.issn.1674-4152.2005.03.002.

相似文献/References:

[1]叶静,肖美添,刘青,等.江蓠藻膳食纤维对衰老小鼠脂质过氧化的影响[J].华侨大学学报(自然科学版),2011,32(1):58.[doi:10.11830/ISSN.1000-5013.2011.01.0058]
　YE Jing,XIAO Mei-tian,LIU Qing,et al.Effect of Gracilaria Dietary Fiber on Lipid Peroxides Activity in Senile Mice[J].Journal of Huaqiao University(Natural Science),2011,32(6):58.[doi:10.11830/ISSN.1000-5013.2011.01.0058]

备注/Memo

备注/Memo:
福建省科技计划重点项目(2008N0120); 泉州市科技计划重点项目(2008G6)
更新日期/Last Update: 2014-03-23