[1]赵鹏,黄颖芬,韦莹莹,等.樟脑不对称还原制备右旋龙脑小试[J].华侨大学学报(自然科学版),2011,32(2):188-190.[doi:10.11830/ISSN.1000-5013.2011.02.0188]
　ZHAO Peng,HUANG Ying-fen,WEI Ying-ying,et al.Amplified Laboratory Research of Asymmetric Reduction of Camphor to Dextral Borneol[J].Journal of Huaqiao University(Natural Science),2011,32(2):188-190.[doi:10.11830/ISSN.1000-5013.2011.02.0188]
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樟脑不对称还原制备右旋龙脑小试()
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《华侨大学学报（自然科学版）》[ISSN:1000-5013/CN:35-1079/N]

卷:
第32卷
期数:
2011年第2期
页码:
188-190
栏目:
出版日期:
2011-03-20

文章信息/Info

Title:
Amplified Laboratory Research of Asymmetric Reduction of Camphor to Dextral Borneol
文章编号:
1000-5013(2011)02-0188-03
作者:
赵鹏; 黄颖芬; 韦莹莹; 王维德
华侨大学化工学院
Author(s):
ZHAO Peng;  HUANG Ying-fen;  WEI Ying-ying;  WANG Wei-de
College of Chemical Engineering, Huaqiao University, Quanzhou 362021, China
关键词:
右旋龙脑;  樟脑;  不对称;  还原反应
Keywords:
dextral bornyl;  camphor;  asymmetric;  reduction reaction
分类号:
TQ655; TQ463
DOI:
10.11830/ISSN.1000-5013.2011.02.0188
文献标志码:
A
摘要:
通过均匀设计,分别在3 L和5 L的烧瓶中,进行碱金属/无水乙醇体系还原樟脑工艺的放大实验.结果表明:放大后所得的樟脑转化率和龙脑产率比均匀实验时有所降低,但经过二次还原,反应体系趋于稳定.合成龙脑工艺放大后仍然可行,右旋龙脑的最高收率分别达到81.13%和80.58%.红外吸收光谱证实,反应产物为右旋龙脑.
Abstract:
In this paper,an amplified laboratory research was carried out on the basis of the previous study.Results showed that the experimental process led to local overheating easily.At the same time,the reaction system viscosity increased,the mass transfer process was slower and the product yield decreased under the amplified study.However,the experiments proved that the process was still feasible after amplification.In the 3 L and 5 L reaction systems,the maximum yield of dextral borneol reached up to 81.13% and 80.58% respectively.The FTIR spectra also confirmed that the products were dextral borneol.

参考文献/References:

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相似文献/References:

[1]王宁辉,赵鹏,王维德,等.樟脑手性合成右旋龙脑[J].华侨大学学报(自然科学版),2006,27(1):89.[doi:10.3969/j.issn.1000-5013.2006.01.024]
　Wang Ninghui,Zhao Peng,Wang Weide,et al.Chiral Reduction of Camphor into D-Borneol[J].Journal of Huaqiao University(Natural Science),2006,27(2):89.[doi:10.3969/j.issn.1000-5013.2006.01.024]
[2]王维德,黄颖芬,王宁辉,等.天然脑粉不对称还原制右旋龙脑[J].华侨大学学报(自然科学版),2007,28(4):410.[doi:10.3969/j.issn.1000-5013.2007.04.020]
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备注/Memo

备注/Memo:
福建省重点科技计划项目(2007Y0027); 华侨大学科研基金资助项目(06X0085)
更新日期/Last Update: 2014-03-23