[1]王小莉,连惠婷,孙向英,等.黄嘌呤分子印迹电化学微传感器的响应特性[J].华侨大学学报(自然科学版),2013,34(6):655-661.[doi:10.11830/ISSN.1000-5013.2013.06.0655]
　WANG Xiao-li,LIAN Hui-ting,SUN Xiang-ying,et al.Response Performance of Molecular Imprinted Polymers Based on Electrochemical Microsensor for Xanthine[J].Journal of Huaqiao University(Natural Science),2013,34(6):655-661.[doi:10.11830/ISSN.1000-5013.2013.06.0655]
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黄嘌呤分子印迹电化学微传感器的响应特性()
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《华侨大学学报（自然科学版）》[ISSN:1000-5013/CN:35-1079/N]

卷:
第34卷
期数:
2013年第6期
页码:
655-661
栏目:
出版日期:
2013-11-20

文章信息/Info

Title:
Response Performance of Molecular Imprinted Polymers Based on Electrochemical Microsensor for Xanthine
文章编号:
1000-5013(2013)06-0655-07
作者:
王小莉;  连惠婷;  孙向英;  刘斌
华侨大学 材料科学与工程学院, 福建 厦门 361021
Author(s):
WANG Xiao-li;  LIAN Hui-ting;  SUN Xiang-ying;  LIU Bin
College of Material Science and Engineering, Huaqiao University, Xiamen 361021, China
关键词:
分子印迹聚合物;  电化学传感器;  黄嘌呤;  吡咯;  响应特性;  吸附特性
Keywords:
molecularly imprinted polymers;  electrochemical sensor;  xanthine;  pyrrole;  response performance;  absorption performance
分类号:
O631
DOI:
10.11830/ISSN.1000-5013.2013.06.0655
文献标志码:
A
摘要:
在碳纤维电极上,通过循环伏安法直接制备以吡咯为功能单体,黄嘌呤为模板分子的分子印迹聚合物膜,考察基于此印迹膜的电化学微传感器对黄嘌呤的响应特性.实验结果发现:该印迹膜有利于黄嘌呤在微电极上的氧化,其电极反应是单电子过程,具有良好的特异识别性;黄嘌呤浓度在4.0~60 μmol·L-1和0.08~2.0 mmol·L-1与其氧化峰峰电流有很好的线性关系,检测限达0.25 μmol·L-1.动力学和热力学实验数据表明:印迹膜微传感器对黄嘌呤响应速度较快,模拟Langmuir模型拟合计算的动力学速率常数是0.24 min,小于玻碳印迹膜传感器的0.71 min,印迹因子为14.1,稍大于玻碳印迹膜传感器的9.0,远远高于对其他常见共存物和结构相似物的识别.
Abstract:
A xanthine(XA)molecularly imprinted polymers(MIPs)were directly prepared on carbon fiber microelectrode(CFME), using pyrrole as function matrix, and xanthine as template molecule by cyclic voltammetry. The response performances of the electrochemical microsensor based on the prepared MIPs were investigated. The MIPs catalyzed the oxidation of XA on CFME which exhibit one electron reaction. Good affinity and excellent specific recognization to xanthine were observed from thermodynamic and kinetic adsorption experiments, and a kinetic constant of 0.24 shows a faster response to xanthine on MIPs/CFME compared to MIPs/GCE(0.71). An Imprinting factor of 14.1 were calculated out by isothermal curve fitting data on MIPs/CFME which is much higher than the recognization of the common coexistence and structural similarities, and shows a good imprinting effect closing to MIPs/GCE(9.0). Two linear response of oxidation peak current of xanthine to concentration were obtained, which ranges from 4.0-60 μmol·L-1 and 0.08-2.0 mmol·L-1 with a detection limit of 0.25 μmol·L-1.

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备注/Memo

备注/Memo:
收稿日期: 2013-04-24
通信作者: 刘斌(1963-),男,教授,主要从事电化学传感器的研究.E-mail:bliu@hqu.edu.cn.
基金项目: 国家自然科学基金资助项目(20955001, 21175049, 21275059); 福建省自然科学基金计划资助项目(2011J01049, 2012J01044); 中央高校基本科研业务费专项基金资助项目(JB-ZR1215)
更新日期/Last Update: 2013-11-20