[1]胡译丹,王兆守,吴忻,等.群体感应系统的合成生物学研究进展[J].华侨大学学报(自然科学版),2013,34(2):165-168.[doi:10.11830/ISSN.1000-5013.2013.02.0165]
　HU Yi-dan,WANG Zhao-shou,WU Xin,et al.Research Progress of Synthetic Biology in Quorum-Sensing System[J].Journal of Huaqiao University(Natural Science),2013,34(2):165-168.[doi:10.11830/ISSN.1000-5013.2013.02.0165]
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群体感应系统的合成生物学研究进展()
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《华侨大学学报（自然科学版）》[ISSN:1000-5013/CN:35-1079/N]

卷:
第34卷
期数:
2013年第2期
页码:
165-168
栏目:
出版日期:
2013-03-20

文章信息/Info

Title:
Research Progress of Synthetic Biology in Quorum-Sensing System
文章编号:
1000-5013(2013)02-0165-04
作者:
胡译丹;  王兆守;  吴忻;  方柏山
厦门大学 化学化工学院, 福建 厦门 361021
Author(s):
HU Yi-dan;  WANG Zhao-shou;  WU Xin;  FANG Bai-shan
College of Chemical Engineering, Xiamen University, Xiamen 361005, China
关键词:
合成生物学;  群体感应系统;  细胞浓度控制;  生物被膜信号通路
Keywords:
synthetic biology;  quorum-sensing system;  cell density control;  biofilm signal pathways
分类号:
Q81;Q-1
DOI:
10.11830/ISSN.1000-5013.2013.02.0165
文献标志码:
A
摘要:
群体感应系统通过释放到环境中的信号分子来进行交流,进而协调群体行为,因其结构简单、机理清晰而广泛应用于合成生物学的研究.简要介绍合成生物学的概念,着重阐述基于群体感应系统的合成生物学研究及其在细胞浓度控制、生物被膜信号通路和生物化工领域的应用.最后,探讨群体感应系统研究的不足,并做进一步展望.
Abstract:
Quorum-sensing system coordinates bacterium behaviour via the secretion of specific signaling molecules in a population density-dependent manner. This system is widely used in synthetic biology because of its simple structure and clear mechanism. In this article, the concept of synthetic biology is introduced briefly. This article mainly focuses on synthetic biology basing on quorum-sensing system and its applications in fields of cell density control, biofilm signal pathways and biochemical industry. Finally, limition of study on quorum-sensing system is discussed. And the prospect of future development is presented.

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相似文献/References:

[1]罗巅辉,余劲聪,方柏山.合成生物学的研究方向与应用[J].华侨大学学报(自然科学版),2009,30(1):1.[doi:10.11830/ISSN.1000-5013.2009.01.0001]
　LUO Dian-hui,YU Jin-cong,FANG Bai-shan.Studying Direction and Application of Synthetic Biology[J].Journal of Huaqiao University(Natural Science),2009,30(2):1.[doi:10.11830/ISSN.1000-5013.2009.01.0001]

备注/Memo

备注/Memo:
收稿日期: 2012-06-12
通信作者: 方柏山(1957-),男,教授,主要从事合成生物学的研究.E-mail:fbs@xmu.edu.cn.
基金项目: 国家自然科学基金资助项目(30770059,21076172); 中央高校基本科研业务费专项基金资助项目(2010121050)
更新日期/Last Update: 2013-03-20