[1]李玉双,刘倩,张昱.DNA序列碱基组合的频率矩阵及其应用[J].华侨大学学报(自然科学版),2013,34(3):308-312.[doi:10.11830/ISSN.1000-5013.2013.03.0308]
　LI Yu-shuang,LIU Qian,ZHANG Yu.Frequency Matrix of Nucleotide Combination of DNA Sequences and Its Application[J].Journal of Huaqiao University(Natural Science),2013,34(3):308-312.[doi:10.11830/ISSN.1000-5013.2013.03.0308]
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DNA序列碱基组合的频率矩阵及其应用()
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《华侨大学学报（自然科学版）》[ISSN:1000-5013/CN:35-1079/N]

卷:
第34卷
期数:
2013年第3期
页码:
308-312
栏目:
出版日期:
2013-05-20

文章信息/Info

Title:
Frequency Matrix of Nucleotide Combination of DNA Sequences and Its Application
文章编号:
1000-5013(2013)03-0308-05
作者:
李玉双1;  刘倩1;  张昱2
1. 燕山大学 理学院, 河北 秦皇岛 066004;2. 石家庄邮电职业技术学院 计算机系, 河北 石家庄 050021
Author(s):
LI Yu-shuang1;  LIU Qian1;  ZHANG Yu2
1. School of Science, Yanshan University, Qinhuangdao 066004, China; 2. Department of Computer, Shijiazhuang Post and Telecommunications Technical College, Shijiazhuang 050021, China
关键词:
DNA;  碱基组合;  频率矩阵;  相似性;  编码序列
Keywords:
DNA;  nucleotide combination;  frequency matrix;  similarity;  coding sequence
分类号:
Q332
DOI:
10.11830/ISSN.1000-5013.2013.03.0308
文献标志码:
A
摘要:
基于碱基组合在DNA序列中出现的频率,构造11个物种的β-globin基因第一个外显子的编码序列的频率矩阵.借助矩阵2-范数对11个物种进行相似性比较,并结合柱状图对物种之间的相似性进行分析.研究结果表明:所构造的DNA序列频率矩阵不仅能够反映出DNA序列中碱基及碱基组合的含量分布,而且能够显示出序列碱基突变的情况.
Abstract:
The frequency matrix of coding sequence of the first exon of β-globin gene of eleven species was proposed based on the frequencies of nucleotide combinations in the DNA sequences. The similarity of eleven species was compared with the aid of 2-norm of matrix. Moreover, the similarity analysis was spread among species with column graphs. The results showed that the frequency matrix of DNA sequences not only could reflect the content distribution of nucleotides and nucleotide combinations in DNA sequences, but also could display the mutations of sequences nucleotides.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期: 2012-10-17
通信作者: 李玉双(1980-),女,副教授,主要从事生物数学的研究.E-mail:liyushuang@yeah.net.
基金项目: 国家自然科学基金资助项目(11201409)
更新日期/Last Update: 2013-05-20