[1]李兆乾,林建明,吴季怀,等.PEG致孔快速响应pH/温度双重敏感性PNIPAM/SA水凝胶的制备与性能[J].华侨大学学报(自然科学版),2010,31(6):649-656.[doi:10.11830/ISSN.1000-5013.2010.06.0649]
　LI Zhao-qian,LIN Jian-ming,WU Ji-huai,et al.Preparation and Properties of Fast Responsive pH/Temperature-Sensitive Poly(N-Isopropylacrylamide)/Sodium Alginate Hydrogels by Using PEG as Pore-Forming Agent[J].Journal of Huaqiao University(Natural Science),2010,31(6):649-656.[doi:10.11830/ISSN.1000-5013.2010.06.0649]
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PEG致孔快速响应pH/温度双重敏感性PNIPAM/SA水凝胶的制备与性能()
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《华侨大学学报（自然科学版）》[ISSN:1000-5013/CN:35-1079/N]

卷:
第31卷
期数:
2010年第6期
页码:
649-656
栏目:
出版日期:
2010-11-20

文章信息/Info

Title:
Preparation and Properties of Fast Responsive pH/Temperature-Sensitive Poly(N-Isopropylacrylamide)/Sodium Alginate Hydrogels by Using PEG as Pore-Forming Agent
文章编号:
1000-5013(2010)06-0649-08
作者:
李兆乾; 林建明; 吴季怀; 黄妙良; 陆遥遥; 冷晴
华侨大学材料物理化学研究所
Author(s):
LI Zhao-qian;  LIN Jian-ming;  WU Ji-huai;  HUANG Miao-liang;  LU Yao-yao;  LENG Qing
Institute of Materials Physical Chemistry, Huaqiao University, Quanzhou 362021, China
关键词:
水凝胶;  N-异丙基丙烯酰胺;  温度;  pH;  聚乙二醇;  海藻酸钠;  快速响应
Keywords:
hydrogel;  N-isopropylacrylamide;  temperature;  pH;  poly(ethylene glycol);  sodium alginate;  fast response
分类号:
O648.17
DOI:
10.11830/ISSN.1000-5013.2010.06.0649
文献标志码:
A
摘要:
以聚乙二醇(PEG)为致孔剂,以海藻酸钠(SA)和N-异丙基丙烯酰胺(NIPAM)为原料,制备出具有温度和pH双重敏感性的快速响应水凝胶.研究温度、pH值对凝胶溶胀度,以及PEG用量和分子量对凝胶溶胀速率的影响.结果表明,海藻酸钠的加入能够赋于PNIPAM pH敏感性能,所制备水凝胶的溶胀度随着pH值的改变而改变.在酸性条件下,凝胶溶胀度随SA用量的增加而减小; 在碱性条件下,凝胶溶胀度随SA用量的增加而增大.在酸性和碱性条件下,水凝胶溶胀度都随着PEG用量的增多和PEG分子量的增大而增大,且与传统水凝胶相比,溶胀速率有较大程度的提高.
Abstract:
Fast responsive pH-sensitive and thermo-sensitive poly(N-isopropylacrylamide)/sodium alginate(PNIPAM/SA) hydrogels were synthesized by using poly(ethylene glycol)(PEG) as pore-forming agent,sodium alginate and N-isopropylacrylamide(NIPAM) as raw materials.The effect of temperature on gel swelling ratio was investigated in acidic(pH=1.2) and alkaline(pH=7.8) conditions,the results showed that the gels swelling ratio increased when the temperature rised.At 26 ℃,the effect of pH values on gels swelling ratio and the amount and molecular weight of PEG on gel swelling kinetics were also studied,the results showed that the as-prepared hydrogels have excellent pH-sensitivity,the amount and molecular weight of PEG have a greater impact on gel swelling rate.

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备注/Memo

备注/Memo:
福建省科技重大专项项目(2007HZ0001-3); 福建省科技计划重点项目(2007T0010); 福建省发改委小发明小创造专项项目(2007年度)
更新日期/Last Update: 2014-03-23