[1]曾庆友,唐建红,曾明荣.L-脯氨酸/吡啶催化合成肉桂酸[J].华侨大学学报(自然科学版),2009,30(2):235-236.[doi:10.11830/ISSN.1000-5013.2009.02.0235]
　ZENG Qing-you,TANG Jian-hong,ZENG Ming-rong.Synthesis of Cinnamic Acid with the Catalysis of L-Proline/Pyridine[J].Journal of Huaqiao University(Natural Science),2009,30(2):235-236.[doi:10.11830/ISSN.1000-5013.2009.02.0235]
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L-脯氨酸/吡啶催化合成肉桂酸()
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《华侨大学学报（自然科学版）》[ISSN:1000-5013/CN:35-1079/N]

卷:
第30卷
期数:
2009年第2期
页码:
235-236
栏目:
出版日期:
2009-03-20

文章信息/Info

Title:
Synthesis of Cinnamic Acid with the Catalysis of L-Proline/Pyridine
文章编号:
1000-5013(2009)02-0235-02
作者:
曾庆友; 唐建红; 曾明荣
华侨大学化工学院
Author(s):
ZENG Qing-you;  TANG Jian-hong;  ZENG Ming-rong
College of Chemical Engineering, Huaqiao University, Quanzhou 362021, China
关键词:
肉桂酸;  L-脯氨酸;  吡啶;  Knoevenagel缩合反应
Keywords:
cinnamic acid;  L-proline;  pyridine;  Knoevenagel condensation
分类号:
TQ245
DOI:
10.11830/ISSN.1000-5013.2009.02.0235
文献标志码:
A
摘要:
以L-脯氨酸/吡啶为催化剂,正己烷做带水剂,用苯甲醛和丙二酸为原料,经Knoenenagel缩合生成肉桂酸.探讨带水剂的种类、原料比(丙二酸与苯甲醛的量比)、催化剂用量和反应时间等对肉桂酸收率的影响.实验结果表明,合成肉桂酸的最合适条件:原料比为1.0∶0.9,L-脯氨酸用量为丙二酸质量的4.0%,反应时间4 h,在此最佳条件下,肉桂酸的收率达到99.0%.
Abstract:
Cinnamic acid was synthesized from benzaldehyde and malonic acid by knoevenagel condensation with the catalysis of L-proline/pyridine in water-carrying agent hexane.The effect of water-carring agents,mole ratio of malonic acid to benzaldehyde,dosage of catalyst and reaction time on the yield of cinamic acid was discussed.The results show that the optimum conditions are: the mole ratio of malonic acid to benzaldehyde 1.0∶0.9,the dosage of proline 4.0% of the weight of malonic acid and the reaction time 4h,the yield of cinnamic acid is 99.0% under the optimum conditions.

参考文献/References:

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[6] 杨辉琼, 易翔, 苏姣莲. 肉桂酸的合成研究 [J]. 化学世界, 2005(1):38.doi:10.3969/j.issn.0367-6358.2005.01.012.

更新日期/Last Update: 2014-03-23