[1]张光亚,葛慧华,方柏山.两种超嗜热菌基因组中同义密码子使用的分析[J].华侨大学学报(自然科学版),2006,27(2):193-196.[doi:10.3969/j.issn.1000-5013.2006.02.022]
　Zhang Guangya,Ge Huihua,Fang Baishan.Analysis of Synonymous Codon Usage in Two Hyperthermophlles[J].Journal of Huaqiao University(Natural Science),2006,27(2):193-196.[doi:10.3969/j.issn.1000-5013.2006.02.022]
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两种超嗜热菌基因组中同义密码子使用的分析()
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《华侨大学学报（自然科学版）》[ISSN:1000-5013/CN:35-1079/N]

卷:
第27卷
期数:
2006年第2期
页码:
193-196
栏目:
出版日期:
2006-04-20

文章信息/Info

Title:
Analysis of Synonymous Codon Usage in Two Hyperthermophlles
文章编号:
1000-5013(2006)02-0193-04
作者:
张光亚; 葛慧华; 方柏山
华侨大学材料科学与工程学院; 华侨大学材料科学与工程学院 福建 泉州 362021; 福建 泉州 362021
Author(s):
Zhang Guangya;  Ge Huihua;  Fang Baishan
College of Material Science and Engineeringi Huaqiao University, 362021, Quanzhou, China
关键词:
敏捷气热菌;  风产液菌;  密码子使用;  表达水平;  对应分析
Keywords:
Aeropyrum pernix;  Aqui fex aeolicus;  codon usage;  gene expression level;  correspondence analysis
分类号:
Q933; Q78
DOI:
10.3969/j.issn.1000-5013.2006.02.022
文献标志码:
A
摘要:
对两种超嗜热菌敏捷气热菌(Aeropyrum pernix)和风产液菌(Aqui fex aeolicus)的密码子使用进行分析.相对密码子使用值(RSCU)的计算表明,它们在密码子使用上具有一定的相似性,但也有不同的使用模式,导致这一现象的机制可能存在差异.密码子RSCU值对应分析表明,两种菌中高表达基因均具有相对较高的GC含量,但基因表达水平对密码子使用偏好的影响程度却不一样.在A.pernix中,它是造成整个基因组密码子使用偏好的最主要因素,而在A.aeolicus中却不是.
Abstract:
Statistics of codon usage in the genomes of two heperthermophiles Aeropyrum pernix and Aqui fex aeolicus were calculated based on the published genomic DNA sequences. It was found that they were similar in the usage of codon, while they also had different patterns, however the mechanism that caused this might be different. There exits great variation of codon usage among these genes. Correspondence analysis based on the RSCU showed that the higher of the GC content, the higher of the gene expression level, but the extent that gene express level influenced the codon usage bias was different. In A. pernix,it was the most important factor that shaped the codon usage patterns, but not in A. aeolicus.

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相似文献/References:

[1]张光亚,方柏山.敏捷气热菌密码子及AUG侧翼序列保守性分析[J].华侨大学学报(自然科学版),2004,25(2):192.[doi:10.3969/j.issn.1000-5013.2004.02.021]
　Zhang Guangya,Fang Baishan.Analysing the Coden and the Conservative Character of AUG Context in Aeropyrum pernix[J].Journal of Huaqiao University(Natural Science),2004,25(2):192.[doi:10.3969/j.issn.1000-5013.2004.02.021]

备注/Memo

备注/Memo:
国务院侨务办公室科研基金资助项目(05Q0018)
更新日期/Last Update: 2014-03-23